Yorkton RCMP are searching for a missing five-year-old girl and her 70-year-old grandmother.

Aires Hotomanie and her grandmother Patricia Mandeville were last seen Friday around 3 p.m. leaving a home in Rhein, Sask. in a white Dodge Caravan. They were reported missing late that night.

RCMP are concerned because the grandmother has health issues and because it’s not typical for the pair to go so long without contacting family or friends.

“Police do not have any indication that any harm has come to either the girl or her grandmother,” an RCMP media release read.

Hotomanie is described as thin, three-feet tall and aboriginal with a mole on her right cheek and brown hair down to her mid-back. She was last seen wearing purple shorts, a pink tank top with spaghetti straps and pink flip-flop sandals.

Mandeville is described as a 5-3, 170-pound aboriginal woman with a medium build, short white hair and glasses. She was last seen wearing a maroon skirt, a black long-sleeve top and coloured elastics on her wrists. She has difficulty walking, RCMP said.

Mandeville is from Winnipeg, according to police. Her granddaughter is from Rhein, a community located about 30 kilometres northeast of Yorkton.

The Dodge Caravan the pair were last seen in has a Manitoba licence plate — HCE 965. The van has a black bra over the hood and coloured necklace beads hanging from the rear-view mirror.

Anyone with information on their whereabouts is asked to contact Yorkton RCMP at 306 786 4500 or Crime Stoppers at 1 800 222 8477.